January 2009
28 posts
[Original articles] Management of neonatal... →
Aim: To ascertain the present management of neonatal abstinence syndrome (NAS) in neonatal units in the United Kingdom (UK) and Ireland.
Methods: Postal questionnaire to 235 neonatal units,…
[Original articles] Permissive Hypotension in The... →
Introduction: Many practitioners routinely treat infants whose mean arterial blood pressure (BP) in mm Hg is less than their gestational age in weeks (GA).
Objective: To assess the…
[Leading articles] Measuring the performance of an... →
Most district general hospital (DGH) paediatricians will have referred critically ill children to a retrieval team at some point in their practice. Inter-hospital transport services have developed…
Out of country until 1st week of April 2009 →
This is for the kind information of visitors to this blog and the parents of my regular patients. I apologise for any inconvenience my absence from the country is causing them.
I am currently out…
[Original articles] Markers that predict serious... →
Objective: To evaluate potential markers of serious bacterial infection (SBI) in infants under 3 months of age presenting with fever of unknown origin.
Material and methods: We retrospectively…
[Original articles] Toxic Additives in Medications... →
Background and objectives: Little is known about exposure of preterm infants to excipients during routine clinical care. The primary objective of this study was to document excipient exposure in…
[Original articles] Problem behaviours and... →
Background: Problems with sleep, eating and adherence to therapy may adversely affect health outcomes in children with cystic fibrosis (CF). Data about prevalence of such problems, associated…
[Original articles] Therapeutic hypothermia can be... →
Background: Therapeutic hypothermia is a safe and effective therapy for neonatal encephalopathy in an intensive care setting; development of simple and safe cooling methods for use in…
[Original articles] Detection of human bocavirus... →
Background: HBoV, a recently discovered parvovirus, is present in a substantial proportion of respiratory tract diseases of suspected infectious origin. The relative importance of HBoV in viral…
[Original articles] Parental reporting of... →
Objectives: To determine the feasibility of parental reporting of suspected adverse drug reactions (ADRs) in their children to community pharmacies in Nigeria.
Methods: Fifteen registered…
[Review] Therapeutic recreation camps →
Chronic illness in early life (<18 yrs)is unexpected, affecting only 2-4% in the western world. Therapeutic recreation (TR) camps have developed to help with normalisation, development of…
[Original articles] Unchanged incidence of... →
Aims: To prospectively determine the change in prevalence of microalbuminuria (MA) in relation to changes in glycaemic control in children diagnosed with type 1 diabetes between 1986 and 1996.
[Original articles] Long-term skin scarring and... →
Objective: to assess the incidence of skin scarring and orthopaedic sequelae (amputation, limb-length discrepancy) in patients who survived meningococcal septic shock (MSS) in childhood and to…
[Leading articles] The search for new asthma... →
There is a longstanding recognition that asthma is a variable disease and attempts to elucidate the causes of asthma have been hampered by its genetic and phenotypic heterogeneity. The recognition…
[Papers] Interleukin-6 G(-174)C polymorphism is... →
Objective: The foetal inflammatory response syndrome including proinflammatory cytokines like interleukin-6 (IL-6) has been associated with cystic periventricular leukomalacia (cPVL). We…
[Review] Therapeutic recreation camps →
Chronic illness in early life (<18 yrs)is unexpected, affecting only 2-4% in the western world. Therapeutic recreation (TR) camps have developed to help with normalisation, development of…
[Leading articles] Delivery of the Paediatric... →
Medical education and the service in which it is embedded, is undergoing radical changes. A new postgraduate paediatric curriculum has been introduced in the United Kingdom which is competency…
[Papers] Benign recurrent sixth (abducens) nerve... →
Sixth nerve palsy can occur as a result of elevated intracranial pressure, neoplasm or trauma. Reports from tertiary centers indicate between 5-16% of cases referred have no etiology ascribed and…
[Original articles] The incidence and aetiology of... →
Objective: To estimate the incidence and describe the aetiology of epistaxis in infants.
Design: Population-based study including a retrospective hospital admission database analysis and a…
[Original articles] UK childhood exposures to... →
Objective: There are no systematic methods for toxicovigilance of non-medicinal products in the UK. This is particularly relevant for pesticides where there is significant public concern about…
[Original articles] Effect of Adenoidectomy on... →
Objective: Risk of childhood asthma is increased in children with recurrent otitis media. This may be associated with recurrent respiratory tract infections in these children, but the role of…
[Original articles] The influence of types of... →
Objective: To determine whether physicians’ posttest probability estimates are influenced by receiving test characteristics and impact their subsequent clinical decisions.
Design:…
[Original articles] Emergency management of... →
Objective: To audit current UK practice of the management of severe sepsis in children against the 2002 American College of Critical Care Medicine / Pediatric Advanced Life Support (ACCM-PALS)…
[Original articles] Do babies with isolated single... →
Background: Presence of isolated single umbilical artery (SUA) has been associated with an increased risk of occult renal malformations. However, the need for routine postnatal renal imaging of…
[Original articles] Early discharge with tube... →
Objective: Mothers of preterm infants are more likely to discontinue breastfeeding early than mothers of term infants. We evaluated the effect of Early Discharge with tube feeding of preterm…
[Original articles] Randomized crossover trial of... →
Background: Apnoea of prematurity (AOP) is a common problem in preterm infants, which may be treated with various modes of nasal continuous positive airway pressure (NCPAP) or nasal intermittent…
[Review] Histologic chorioamnionitis and... →
A considerable body of human and animal experimental evidence links antenatal inflammation to both accelerated maturation and adverse development of the lung. Initial reports suggest that in…
[Review] Controlling an outbreak of MRSA in the... →
Meticillin Resistant Staphylococcus Aureus (MRSA) can cause serious infections in the newborn. While audit may show that a Neonatal Unit’s main cause of infective morbidity is the coagulase…