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May 10

The role of inhaled corticosteroids and montelukast in children with mild-moderate asthma: results of a systematic review with meta-analysis - Objective

To compare the efficacy of inhaled corticosteroids (ICS) versus montelukast (MONT) in schoolchildren and adolescents with mild–moderate persistent asthma.

Methods

Randomised,…

Sirolimus and tuberous sclerosis-associated renal angiomyolipomas -

Tuberous sclerosis, caused by germline mutations in the TSC1 or TSC2 genes, is associated with aberrant upregulation of the mammalian target of rapamycin (mTOR) signalling pathway, resulting in…

Question 1 Do lycra garments improve function and movement in children with cerebral palsy?

Towards evidence based medicine for paediatricians

Does sweat volume influence the sweat test result? - Objective

Low volume sweat samples are considered unreliable for the diagnosis of cystic fibrosis, based on the assertion that sweat conductivity and chloride are reduced at lower sweating rates….

Infant feeding practice and childhood cognitive performance in South India - Aim

Several studies have suggested a beneficial effect of infant breastfeeding on childhood cognitive function. The main objective was to examine whether duration of breastfeeding and age at…

The epidemiology of progressive intellectual and neurological deterioration in childhood - Objective

To study the epidemiology of diseases that cause progressive intellectual and neurological deterioration (PIND) in UK children.

Design

Since May 1997, the authors have performed active…

Recent skin injuries in children with motor disabilities - Objective

To determine the frequency of recent skin injuries in children with neuromotor disabilities and its association with disability.

Design

Cross-sectional study of 168 children with…

Developmental and epilepsy outcomes at age 4 years in the UKISS trial comparing hormonal treatments to vigabatrin for infantile spasms: a multi-centre randomised trial - Background

Infantile spasms is the name given to a difficult to treat, severe infantile epilepsy with high morbidity. The United Kingdom Infantile Spasms Study (UKISS) showed that absence of…

Contribution of bacteriology and virology in sudden unexpected death in infancy - Objective

To appraise the inter-agency protocol used in sudden unexpected death in infancy (SUDI) cases in South Yorkshire, UK.

Design

A retrospective audit of 121 postmortems carried out over a…

What are the clinical and radiological characteristics of spinal injuries from physical abuse: a systematic review - Aim

Systematic review of ‘What are the clinical and radiological characteristics of inflicted spinal injury?’

Methods

Literature search of 20 electronic databases, websites, references and…